Abstract Background: Early onset dementia (EOD) is defined as dementia with symptoms onset before 65 years. Little is known about the etiological role of environmental and occupational risk factors. We aimed at assessing the role of these factors in disease
Poster: Exposure to particulate matter and risk of amyotrophic lateral sclerosis: A case-control study in Northern Italy
Abstract Background: Amyotrophic lateral sclerosis (ALS) is progressive neurodegenerative disease with still unknown etiology. Role of occupational and environmental risk factors has been investigated, including outdoor air pollutants, which have been recently associated to an excess disease risk. We carried
Original article: Common cardiovascular risk factors and in-hospital mortality in 3,894 patients with COVID-19: survival analysis and machine learning-based findings from the multicentre Italian CORIST Study
Di Castelnuovo A, Bonaccio M, Costanzo S, Gialluisi A, Antinori A, Berselli N, Blandi L, Bruno R, Cauda R, Guaraldi G, My I, Menicanti L, Parruti A, Patti G, Perlini S, Santilli F,Signorelli C, Stefanini GG, Vergori A, Abdeddaim A,
Poster: The epidemiology of the different clinical presentations of early onset dementia
Abstract Background: It is known that patients with Early Onset Dementia (EOD), defined as dementia with symptoms onset before the age of 65, frequently present with atypical clinical syndromes. However, the epidemiology of the different presentations of EOD, including the clinical
Original article: Lockdown timing and efficacy in controlling COVID-19 using mobile phone tracking
Vinceti M, Filippini T, Rothman KJ, Goffi A, Ferrari F, Maffeis G, Orsini N EClinicalMedicine. 2020:100457 – DOI: 10.1016/j.eclinm.2020.100457 Abstract Background: Italy’s severe COVID-19 outbreak was addressed by a lockdown that gradually increased in space, time and intensity. The effectiveness
Original article: Cadmium exposure and risk of breast cancer: A dose-response meta-analysis of cohort studies
Filippini T, Torres D, Lopes C, Carvalho C, Moreira P, Naska A, Kasdagli MI, Malavolti M, Orsini N, Vinceti M Environ Int. 2020 Jun 26;142:105879 – DOI: 10.1016/j.envint.2020.105879 Abstract Background: Cadmium is a toxic heavy metal that has been implicated in
Original article: Satellite-detected tropospheric nitrogen dioxide and spread of SARS-CoV-2 infection in Northern Italy
Filippini T, Rothman KJ, Goffi A, Ferrari F, Maffeis G, Orsini N, Vinceti M Sci Total Environ. 2020; 739:140278 – DOI: 10.1016/j.scitotenv.2020.140278 Abstract Following the outbreak of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) last December 2019 in China, Italy was
Original article: Lead exposure in an Italian population: Food content, dietary intake and risk assessment
Malavolti M, Fairweather-Tait SJ, Malagoli C, Vescovi L, Vinceti M, Filippini T Food Res Int. 2020;137:109370 – DOI: 10.1016/j.foodres.2020.109370 Abstract Background and aim: Lead is a highly toxic heavy metal released into the environment after natural and anthropogenic activities. Excluding populations
Original article: Potassium intake and blood pressure: A dose-response meta-analysis of randomized controlled trials
Filippini T, Naska A, Kasdagli MI, Torres D, Lopes C, Carvalho C, Moreira P, Malavolti M, Orsini N, Whelton PK, Vinceti M J Am Heart Assoc. 2020 Jun 5:e015719. DOI: 10.1161/JAHA.119.015719 Abstract Background: Epidemiologic studies, including trials, suggest an association
Original article: The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis
Violi F , Solovyev N , Vinceti M , Mandrioli J , Lucio M , Michalke B Metallomics. 2020 May 27;12(5):668-681 – DOI: 10.1039/d0mt00051e Abstract Amyotrophic lateral sclerosis is a progressive neurodegenerative disease characterized by a loss of function of